Tuscaloosa Zip Codes: Complete Breakdown of Every Area (2026) Quick answer: Tuscaloosa, Alabama has nine ZIP codes. The four you will see on an actual street address are 35401 (downtown and the University of Alabama), 35404 (east Tuscaloosa), 35405 (south Tuscaloosa) and 35406 (north Tuscaloosa). 35487 is a unique ZIP code used only for University … Continue reading Tuscaloosa Zip Code Map & Complete Area Guide